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Title: Is race real???
Description: A fascinating look at genetics


Merin Sun - July 11, 2003 04:55 PM (GMT)
http://www.cnn.com/2003/US/07/11/nyt.kristof/index.html

OXFORD, England -- I had my DNA examined by a prominent genetic specialist here, and what do you know! It turns out I'm African-American.

The mitochondria in my cells show that I'm descended from a matriarch who lived in Africa, possibly in present-day Ethiopia or Kenya.

O.K., this was 70,000 years ago, and she seems to be a common ancestor of all Asians as well as all Caucasians. Still, these kinds of DNA analyses illuminate the raging scientific debate about whether there is anything real to the notion of race.

"There's no genetic basis for any kind of rigid ethnic or racial classification at all," said Bryan Sykes, the Oxford geneticist and author of "The Seven Daughters of Eve." "I'm always asked is there Greek DNA or an Italian gene, but, of course, there isn't. . . . We're very closely related."

Likewise, The New England Journal of Medicine once editorialized bluntly that "race is biologically meaningless."

Take me. Dr. Sykes looked at a sequence of my mitochondrial DNA to place me on a kind of global family tree. It would have been nice to learn that my ancestors hailed from a village on Loch Ness, but ancestry can almost never be pegged that precisely, and I appear to be a mongrel. One of my variants, for example, is scattered among people in Finland, Poland, Armenia, the Netherlands, Scotland, Israel, Germany and Norway.

On the other hand, is race really "biologically meaningless"? Bigotry has been so destructive that it's tempting to dismiss race and ethnicity as artificial, but there are genuine differences among population groups.

Jews are more likely to carry mutations for Tay-Sachs, Africans for sickle cell anemia. It's hard to argue that ethnicity is an empty concept when one gene mutation for an iron storage disease, hemochromatosis, affects fewer than 1 percent of Armenians but 8 percent of Norwegians.

"There is great value in racial/ ethnic self-categorizations" for medicine, protested an article last year by a Stanford geneticist, Neil Risch, in Genome Biology. It warned against "ignoring our differences, even if with the best of intentions."

DNA does tend to differ, very slightly, with race. Profilers thought a recent serial killer in Louisiana was white until a DNA sample indicated he was probably black. (A black man has been arrested in the case.) As genetic science advances, the police may eventually be able to recover semen and put out an A.P.B. for a tall white rapist with red curly hair, blue eyes and perhaps a Scottish surname.

On the other hand, genetic markers associated with Africans can turn up in people who look entirely white. Indians and Pakistanis may have dark skin, but genetic markers show that they are Caucasians.

Another complication is that African-Americans are, on average, about 17 percent white: they have mitochondria (maternally inherited) that are African, but they often have European Y chromosomes. In other words, white men raped or seduced their maternal ancestors.

Among Jews, there are common genetic markers, including some found in about half the Jewish men named Cohen. But this isn't exactly a Jewish gene: the same marker is also found in Arabs.

"Genetics research is now about to end our long misadventure with the idea of race," Steve Olson writes in his new book, "Mapping Human History."

When I lived in Japan in the 1990's, my son Gregory had a play date with a classmate I hadn't met. I asked Gregory, then 5, whether the boy's mother was Japanese.

"I don't know," Gregory replied.

"Well," I asked sharply, "did she look Japanese or American?" Although he'd lived in Tokyo for years, Gregory replied blankly, "What does a Japanese person look like?"

He was ahead of his time. Genetics increasingly shows that racial and ethnic distinctions are real — but often fuzzy and greatly exaggerated. Genetics will increasingly show that most humans are mongrels, and it will make a mockery of racism.

"There are meaningful distinctions among groups that may have implications for disease susceptibility," said Harry Ostrer, a genetics expert at the New York University School of Medicine. "The right-wing version of this is `The Bell Curve,' and that's pseudoscience — that's not real. But there can be a middle ground between left-wing political correctness and right-wing meanness."

I'll be searching for that middle ground this year as I'm celebrating Kwanzaa.

* * *

Genetic Bazaar

Anyone can get a DNA analysis to try to shed light on genetic origins, but for now don't expect to be pegged too precisely. Bryan Sykes of Oxford University founded a company that offers analyses based on the rubric in his book "The Seven Daughters of Eve," and more information is available at www.Oxfordancestors.com. That's the company I used. An alternative is an American company offering DNA analyses with a genealogy focus, www.familytreedna.com.


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The article had me until they got to this point:

"The right-wing version of this is `The Bell Curve,' and that's pseudoscience — that's not real. But there can be a middle ground between left-wing political correctness and right-wing meanness."

And then I became lost...lol




omichyron - July 24, 2003 05:27 AM (GMT)
obviously there's at least some genetic basis for race. otherwise two chinese people having black kids wouldn't put the wife and the neighbor under a bit of suspicion :P

Instead of asking "does race exist" like many excessively liberal people want us to, perhaps we should be asking "does race matter"? :huh:

kundor - July 25, 2003 06:23 PM (GMT)
When people say that you can't determine race genetically, that's really saying that genetic science hasn't advanced far enough yet, not that it's not there. Once the genome is fully decoded, the pigmentation genes can be found, and skin color and such can be determined genetically.
Nevertheless, the differences really aren't very deep at all--it's not as obvious as we might expect. Race is very superficial.

Merin Sun - July 25, 2003 08:28 PM (GMT)
It's not only skin color that determines a race. Look at Asians, Chinese and Japanese people have black hair, yellowish skin <really white looking to me <shrugs), flat, high foreheads and narrow eyes.

You have Vikings, all thick, tall, burly, hairy...it's the same group of people breeding into each other to create these physical differences. It's a dominate family trait. But what eles also gets passed along within that family along with those physical traits???

The article pointed out that some people, whose only connection to one another is where their blood comes from, have immunities or are subceptible <sp???) to certain diseases. Or they are more likely to have problems with certain things.

If, let's say...Chinese...if Chinese people had kept themselves sealed off from the rest of the world, how far would the dominate traits taken them??? How different would they be from the rest of the world???

Because of better transportation and how everything is connected to everything else, bloodlines are being more mixed and dominate physical traits are being spread out. In a thousand years or so, I think that it would be hard to say "hey, that's a Swede, that's a Japanese". So, in that sense race is becoming less definable and less important.

But when transportation was very poor, differences in one group of people was very sharp. So, race mattered then b/c it defined a people.

So, in conclusion...classifying race is important now because we can define "race" but it certainly won't be important later on.

Matrim Cauthon - July 26, 2003 06:01 AM (GMT)
So why is this in the Entertainment section?

Merin Sun - July 26, 2003 06:39 AM (GMT)
Um...well...I'm entertained...

good question...I thought i had put this under the War Dept...whoops...

:o

kundor - July 26, 2003 11:59 PM (GMT)
QUOTE (Merin Sun @ Jul 25 2003, 03:28 PM)
Because of better transportation and how everything is connected to everything else, bloodlines are being more mixed and dominate physical traits are being spread out. In a thousand years or so, I think that it would be hard to say "hey, that's a Swede, that's a Japanese". So, in that sense race is becoming less definable and less important.

But when transportation was very poor, differences in one group of people was very sharp. So, race mattered then b/c it defined a people.

Actually, back when transportation was bad, race didn't matter much at all, because there wasn't much interaction. They didn't have the mindset or the words for race: there were really just locals and strangers. Hence, Africans became Roman Emperors, and that wasn't considered any stranger than a Spaniard becoming Emperor: Neither is roman, so both are foreign. Race as a concept didn't show up til much later, when advanced transportation and large-scale contact began occuring.

Merin Sun - July 27, 2003 02:42 AM (GMT)
Well...the point I was trying to make is that you could look at an olive skinned person and know they come from a Middle Eastern region...or if you look at a very pale person you know they're a Brit :P

You can't look at black person today in Cincinnati and say "They're African" b/c they're not, they are American.

<shrugs>

QueenSmarmyPants - January 29, 2004 08:33 AM (GMT)
Actually the propensity to pop out a white kid is there in the blackest people, and vice versa, as of course thats how traits got started... as well as epicanthic folds (asian eyes) which appear among some African groups, etc. etc. "Race" in humans is rather less telling genetically than "breed" in dogs.

Dorothy - January 29, 2004 08:34 AM (GMT)
We are all one race in the eyes of our Lord and Saviour.

omichyron - January 29, 2004 09:03 AM (GMT)
QUOTE (Dorothy @ Jan 29 2004, 08:34 AM)
We are all one race in the eyes of our Lord and Saviour.

the rat race :naughty:

KaneDragon - January 29, 2004 08:15 PM (GMT)
I remain highly skeptic of the precision of this DNA heritage analysis Merin described.


For the subject of genetics, I whole-heartedly recommend Genome, by Matt Ridley. It's an interesting book.

Living with Our Genes is a book I discovered by reading the bibliography-thing at the back of Genome. It's far more pop-sci than Genome, with less facts, bigger print, and fewer pages. Still, it had a good flow for me and may be worth looking into, as well.




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